3/02/2025 – The european uCAIR (Ultra-fast Chemical Analysis Imaging with Raman) project is pursuing its ambition to transform cancer diagnosis using cutting-edge photonics technology. Led by the University of Limerick, the project aims to develop a real-time imaging system that can identify biomarkers in biofluids and tissues without the need for contrast agents. This revolutionary approach could replace time-consuming biopsy analyses with immediate detection of cellular anomalies, enabling faster and more accurate medical decisions.
A major breakthrough was recently achieved by Photonics Bretagne’s fibre team, with the optical characterisation of a new microstructured optical fibre dedicated to the generation of supercontinuum coherent signals. This fibre will be integrated by partner Multitel into its laser, paving the way for an initial clinical demonstration by the end of the year. A decisive step towards faster, more accurate diagnostics!
A look back at the last two strategy meetings with all 11 project partners (University of Limerick (coordinator), Lambda-X High-Tech, LLS ROWIAK LaserLabSolutions GmbH, Leibniz-Institut für Photonische Technologien, Friedrich-Schiller-Universität Jena, Multitel, Altınbaş Üniversitesi, VDI/VDE Innovation + Technik GmbH, Photonics Bretagne, Institute of Scientific Instruments of the CAS, and Femto-St/CNRS):
▪️ First meeting (October 2024, Nivelles, Belgium): This first technical review brought together all the partners to assess progress and define the next steps. The main objectives of the project were reaffirmed: the development of the ultra-fast λ-Scan laser, the development of the AI-based expert system, and the installation of a prototype microscope. Photonics Bretagne’s involvement in the characterisation of optical fibres was hailed as a key factor in the technical success.
▪️ Second meeting (January 2025, Brno, Czech Republic): This meeting marked the start of the second year of the project, with particular attention paid to the integration of the various modules of the Raman imaging platform. At the same time, complex samples for comparative analysis are being prepared, in particular biological tissues and body fluids. On the software side, work is also progressing on the AI system for image reconstruction.
Perspectives and impact on medical diagnosis
The advances made as part of the uCAIR project open up promising prospects for cancer diagnosis. The combination of hyperspectral imaging, ultra-fast lasers and artificial intelligence should enable early and reliable detection of cancer cells, reducing the need for invasive biopsies and improving the speed of diagnosis.
Photonics Bretagne is playing a key role in this initiative by contributing its expertise in advanced optical fibres. Its involvement in the design of fibres for supercontinuum generation will contribute directly to the precision and efficiency of the imaging system.
With a first clinical demonstration planned by the end of 2025, uCAIR is positioned as a key project for the medicine of tomorrow. Photonic innovation in the service of health takes on its full meaning here, offering real hope for patients and healthcare professionals.